Sonntag, 2. August 2009

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Mittwoch, 16. Januar 2008

calcium supplemenentation: myocardial infarction, stroke, or sudden death

Vascular events in healthy older women receiving calcium supplementation: randomised controlled trial -- Bolland et al., 10.1136/bmj.39440.525752.BE -- BMJ (free)
Conclusion: Calcium supplementation in healthy postmenopausal women is associated with upward trends in cardiovascular event rates. This potentially detrimental effect should be balanced against the likely benefits of calcium on bone. Setting: Academic medical centre in an urban setting in New Zealand.
(published 15 January 2008)

Dienstag, 15. Januar 2008

Bridging therapy (perioperative heparin)

Arch Intern Med -- Venous Thromboembolism and the Archives of Internal Medicine, 1908 to 2005, January 14, 2008, Dalen 168 (1): 14
.... The incidence of postoperative VTE was decreased by 55% in patients treated with fondaparinux, but the incidence of bleeding was increased. ...

Arch Intern Med. 2008;168(1):63-69. Free abstract; full text requires subscription
Risk of Thromboembolism With Short-term Interruption of Warfarin Therapy
Conclusions: For many patients receiving long-term anticoagulation who need to undergo a minor outpatient intervention, a brief (5 days) periprocedural interruption of warfarin therapy is associated with a low risk of thromboembolism. The risk of clinically significant bleeding, even among outpatients undergoing minor procedures, should be weighed against the thromboembolic risk of an individual patient before the administration of bridging anticoagulant therapy.

Montag, 14. Januar 2008

transfer of youth to the adult criminal justice system: counterproductive

Effects on Violence of Laws and Policies Facilitating the Transfer of Youth from the Juvenile to the Adult Justice System Morbidity and Mortality Weekly Report , November 30, 2007 / Vol. 56 / No. RR-9 The MMWR series of publications is published by the Coordinating Center for Health Information and Service, Centers for Disease Control and Prevention (CDC), U.S. Department of Health and Human Services, Atlanta, GA 30333
Review of the effects of transfer laws on subsequent violence indicates that the experience of transfer to the adult criminal justice system is associated with subsequent violence among juvenile participants when compared with violence among juveniles retained in the juvenile justice system. In addition, little evidence supports the idea that transfer laws deter juveniles in the general population from violent crime. These policies might be favored by policymakers or the public for other reasons (e.g., societal retribution in response to serious crime or incapacitation of serious offenders). However, the review indicates that use of transfer laws and strengthened transfer policies is counterproductive to reducing juvenile violence and enhancing public safety.